Adrenergic Receptor
Beta Receptor
Adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine and epinephrine. Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes widening the pupils of the eye, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle. There are two main groups of adrenergic receptors, α and β, with several subtypes. α receptors have the subtypes α1 and α2. β receptors have the subtypes β1, β2 and β3. All three are linked to Gs proteins, which in turn are linked to adenylate cyclase. Agonist binding thus causes a rise in the intracellular concentration of the second messenger cAMP. Downstream effectors of cAMP include cAMP-dependent protein kinase (PKA), which mediates some of the intracellular events following hormone binding.
Adrenergic Receptor Isoform Specific Products
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Adrenergic Receptor Inhibitors
(267)
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Adrenergic Receptor Agonists
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Adrenergic Receptor Antagonists
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Adrenergic Receptor Activators
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Adrenergic Receptor Modulators
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Adrenergic Receptor Degrader
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Adrenergic Receptor Controls
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Adrenergic Receptor Substrates
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Adrenergic Receptor Ligands
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Adrenergic Receptor Related Products (1620)
Related Products (1620)
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Antibodies (4)
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Adrenergic Receptor Isoform Comparison
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L-770644 dihydrochloride
0 ImagesCat. No.: HY-124208ACAS No.: 182251-68-9L-770644 is an orally active, potent and selective agonist of the human β3 adrenergic receptor (EC50 = 13 nM).
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O-Desmethyl Mebeverine alcohol hydrochloride (Standard)
0 ImagesCat. No.: HY-G0008ARCAS No.: 856620-39-8Synonyms: Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride (Standard)Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate. This product is intended for research and analytical applications. Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments.
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Trecadrine
0 ImagesCat. No.: HY-U00303CAS No.: 90845-56-0Synonyms: TrecadrinumTrecadrine is a β3-adrenergic agonist.
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Benzquinamide
0 ImagesBenzquinamide (P2647; BZQ; Benzoquinamide) is an orally active binder of dopamine receptors and adrenergic receptors. Benzquinamide specifically targets dopamine D2, D3, D4 receptors and α-2A, α-2B, α-2C adrenergic receptors. Benzquinamide regulates blood pressure and heart rate, attenuates the pressor effect of adrenaline, and exhibits activities such as antiemesis, anxiolysis, and reduction of histamine-induced bronchoconstriction. Benzquinamide has good safety and does not deplete serotonin or norepinephrine in the brain. Benzquinamide can be used in studies related to nausea/vomiting, mental disorders, anxiety states, neurosis, and psychosis.
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β3-AR agonist 2
0 ImagesCat. No.: HY-U00391CAS No.: 340757-05-3β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM.
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QF0301B
0 ImagesCat. No.: HY-101690CAS No.: 149247-12-1QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.
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Tertatolol
0 ImagesCat. No.: HY-U00356CAS No.: 83688-84-0Synonyms: (±)-Tertatolol; Racemic Tertatolol; dl-TertatololTertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
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(4E)-SUN9221
0 ImagesCat. No.: HY-U00367CAS No.: 222318-55-0(4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
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α1 adrenoceptor-MO-1
0 ImagesCat. No.: HY-U00333CAS No.: 161905-64-2α1 adrenoceptor-MO-1, an S enantiomer, has affinity at alpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.
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D2343
0 ImagesCat. No.: HY-U00206CAS No.: 72734-63-5D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
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Epanolol
0 ImagesCat. No.: HY-U00183CAS No.: 86880-51-5Synonyms: Visacor; ICI141292Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
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Fiduxosin
0 ImagesCat. No.: HY-U00399CAS No.: 208993-54-8Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.
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MG 1
0 ImagesCat. No.: HY-U00110CAS No.: 148274-76-4MG 1 is an α1 adrenergic receptor antagonist.
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Tropodifene
0 ImagesCat. No.: HY-U00313CAS No.: 15790-02-0Synonyms: TropaphenTropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.
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5-HT2 antagonist 1
0 ImagesCat. No.: HY-U00365CAS No.: 191592-09-35-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.
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GP2-114
0 ImagesCat. No.: HY-U00191CAS No.: 130783-39-0GP2-114 (GP-2-114) produces current-dependent cardiovascular action when administered by transdermal iontophoresis.
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ZK-90055 hydrochloride
0 ImagesCat. No.: HY-U00293CAS No.: 84638-81-3ZK-90055 hydrochloride is a β2 adrenergic receptor agonist.
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Fenmetozole Tosylate
0 ImagesCat. No.: HY-U00402CAS No.: 83474-08-2Fenmetozole Tosylate is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor, and acts as an antidepressant agent.
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AR-08
0 ImagesCat. No.: HY-U00371CAS No.: 226081-74-9AR-08 is an agonist of α2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD).
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Bometolol Hydrochloride
0 ImagesCat. No.: HY-U00386CAS No.: 65023-16-7Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
